Safety and effectiveness of exercise interventions for kinesiophobia in patients with cardiovascular disease: a systematic review and meta-analysis

Exploratory subgroup analyses detected numerical differences in pooled effect sizes across different exercise parameters, yet these observational trends cannot support definitive exercise recommendations due to small sample sizes.</p> <p>Exercise to reduced kinesiophobia in cardiovascular patients, limited safety records and substantial heterogeneity across moderate-quality evidence restrict definitive inferences.</p> <p>PRISMA 2020 statement.</p> <p>CRD42025646414</p> <p></p><p>Exercise can improve the physical condition of patients with cardiovascular disease and reduce their fear of exercise.</p><p>Patients with high levels of exercise phobia need supplementary psychological counseling in addition to rehabilitation training to further enhance the effectiveness of rehabilitation in alleviating anxiety.</p><p>Real-time monitoring of vital signs during all exercise helps identify and manage minor adverse reactions, thereby reducing patient avoidance of exercise and enhancing patient safety.</p><p>Medical staff should use validated tools to regularly and systematically screen patients for exercise phobia upon admission for timely and targeted intervention.</p><p>Combining structured exercise programs with specific health education can correct patients’ misconceptions about the risks of physical activity.</p><p></p> <p>Exercise can improve the physical condition of patients with cardiovascular disease and reduce their fear of exercise.</p> <p>Patients with high levels of exercise phobia need supplementary psychological counseling in addition to rehabilitation training to further enhance the effectiveness of rehabilitation in alleviating anxiety.</p> <p>Real-time monitoring of vital signs during all exercise helps identify and manage minor adverse reactions, thereby reducing patient avoidance of exercise and enhancing patient safety.</p> <p>Medical staff should use validated tools to regularly and systematically screen patients for exercise phobia upon admission for timely and targeted intervention.</p> <p>Combining structured exercise programs with specific health education can correct patients’ misconceptions about the risks of physical activity.</p>