Fragile X Disorders among Nigerian Children with neurodevelopmental delays and women with suspected Fragile X-associated Primary Ovarian Insufficiency

The study hypothesized that Fragile X-related mutations are underrecognized in Nigeria. The dataset includes sociodemographic, clinical, and molecular genetic data obtained through clinical assessment and FMR1 PCR-based testing.

Children screened had autism, intellectual disability, developmental delay, and related disorders, while women had features suggestive of FXPOI. The data demonstrates the feasibility of targeted Fragile X screening in Nigeria and provide insight into the clinical presentation and distribution of Fragile X-related mutations in an understudied African population.