Structure · dataset · 2026
Design of Experiments for Diverse Carbon Isotope Labeling with Aryl Thianthrenium Salts
Listed in ZivaHub
A method for accessing structurally diverse carbon-isotope-labeled products from aryl thianthrenium salts has been established.
Description
The use of near-stoichiometric amounts of <i>ex situ</i>-generated carbon monoxide along with simple, air-stable palladium catalysts allows for the synthesis and isotope labeling of a broad range of carbonylation products. Design of Experiments enabled rapid optimization and gain of key mechanistic insight.
The reaction tolerates electronically diverse electrophiles and could be used for the synthesis and late-stage isotope labeling of several pharmaceutical molecules.
Links
Where it is published
- DOI doi.org/10.1021/acs.orglett.6c03866.s001 ↗
DOI / persistent id · from zivahub uct ac za
Catalogue records · 1
- OAI-PMH record api.figshare.com/v2/oai?verb=GetRecord&metadataPrefix=oai_dc&identifier=oai%3Af… ↗
metadata API · from zivahub uct ac za
Topics
Provenance · 1 source records, 14 field assertions
| Source | Key | Last seen | Raw |
|---|---|---|---|
| ZivaHub | oai:figshare.com:article/34024586 | 13 d ago | JSON v1 |
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|---|---|---|---|
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| concepts[field].local:field:medicine-health | mapping · zivahub uct ac za | connector:zivahub_uct_ac_za@1.0.0 | |
| description | source · zivahub uct ac za | connector:zivahub_uct_ac_za@1.0.0 | /metadata/dc/description |
| license | source · zivahub uct ac za | connector:zivahub_uct_ac_za@1.0.0 | /metadata/dc/rights |
| publication_date | source · zivahub uct ac za | connector:zivahub_uct_ac_za@1.0.0 | |
| title | source · zivahub uct ac za | connector:zivahub_uct_ac_za@1.0.0 | /metadata/dc/title |