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Omics · study · 2026

CMPortal: a community-oriented, data-driven resource to inform protocol design for cardiac modelling from human pluripotent stem cells

Listed in NCBI GEO

Protocol design and benchmarking is central to optimise model development using human pluripotent stem cell derived cardiomyocytes (hPSC-CMs).

Description

By applying data mining to decades of research and hundreds of peer reviewed studies, we evaluate how protocol variables associate with common properties of cardiac functional and physiological maturation. This resource is publicly accessible through CMPortal, a community-oriented website providing custom navigation of the database, enabling researchers to benchmark protocol designs and outcomes for their dedicated applications.

It hosts data-driven tools for researchers to leverage decades of knowledge gain across hundreds of hPSC-CM studies to inform strategies for studies in developmental biology, disease modelling, and drug screening.

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From keywords
Life Sciences
Inferred from text
Biochemistry and cell biology 72% · Disease 75% · Heart 65%
Provenance · 1 source records, 10 field assertions
SourceKeyLast seenRaw
NCBI GEOGSE29857315 d agoJSON v1
FieldAssertionExtractorEvidence
access_levelsource · NCBI GEOconnector:ncbi_geo@1.0.0
concepts[anatomy].local:anatomy:heartenrichment · NCBI GEOkeyword-concept-rules@1.0.0title+description (65%)
concepts[disease].local:disease:diseaseenrichment · NCBI GEOkeyword-concept-rules@1.0.0title+description (75%)
concepts[field].anzsrc:group:3101enrichment · NCBI GEOtaxonomy-embedding@1.1.0title+keywords+description (72%)
concepts[field].local:field:life-sciencesmapping · NCBI GEOconnector:ncbi_geo@1.0.0
concepts[method].geo_series_type:expression-profiling-by-high-throughput-sequencingsource · NCBI GEOconnector:ncbi_geo@1.0.0/gdstype
concepts[organism].NCBITaxon:9606source · NCBI GEOconnector:ncbi_geo@1.0.0/taxon
descriptionsource · NCBI GEOconnector:ncbi_geo@1.0.0/summary
publication_datesource · NCBI GEOconnector:ncbi_geo@1.0.0
titlesource · NCBI GEOconnector:ncbi_geo@1.0.0/title