Excel · study · 2026
Prmt1-mediated Otud4 methylation activates the Pabpc1–Scube3 axis to promote bone formation and ameliorate osteoporosis
Listed in NCBI GEO
Osteoporosis is a systemic skeletal disorder characterized by reduced bone mass, deteriorated bone microarchitecture, and elevated fracture risk due to an imbalance between osteoblast-mediated formation and osteoclast-driven resorption.
Description
Although protein arginine methyltransferase 1 (Prmt1) is implicated in skeletal metabolism, its precise functional role in osteoblast biology remains elusive.
Links
Get the data
- GEO FTP directory ftp.ncbi.nlm.nih.gov/geo/series/GSE344nnn/GSE344974 ↗
download · from NCBI GEO
Where it is published
- GEO accession page ncbi.nlm.nih.gov/geo/query/acc.cgi?acc=GSE344974 ↗
landing page · from NCBI GEO
Documentation and papers
- PRJNA1517378 ncbi.nlm.nih.gov/bioproject/PRJNA1517378 ↗
project · from NCBI GEO
Topics
- Stated by source
- Expression profiling by high throughput sequencing · Mus musculus
- From keywords
- Life Sciences
Provenance · 1 source records, 7 field assertions
| Source | Key | Last seen | Raw |
|---|---|---|---|
| NCBI GEO | GSE344974 | 15 d ago | JSON v1 |
| Field | Assertion | Extractor | Evidence |
|---|---|---|---|
| access_level | source · NCBI GEO | connector:ncbi_geo@1.0.0 | |
| concepts[field].local:field:life-sciences | mapping · NCBI GEO | connector:ncbi_geo@1.0.0 | |
| concepts[method].geo_series_type:expression-profiling-by-high-throughput-sequencing | source · NCBI GEO | connector:ncbi_geo@1.0.0 | /gdstype |
| concepts[organism].NCBITaxon:10090 | source · NCBI GEO | connector:ncbi_geo@1.0.0 | /taxon |
| description | source · NCBI GEO | connector:ncbi_geo@1.0.0 | /summary |
| publication_date | source · NCBI GEO | connector:ncbi_geo@1.0.0 | |
| title | source · NCBI GEO | connector:ncbi_geo@1.0.0 | /title |