Omics · study · 2026
Cxcr2 deficiency reshapes the bone marrow transcriptome and is associated with impaired bone homeostasis in adult male mice
Listed in NCBI GEO
C-X-C chemokine receptor 2 (CXCR2) contributes to leukocyte trafficking and inflammatory signaling.
Description
To investigate its role in skeletal homeostasis, we profiled the femoral bone marrow transcriptome of adult male Cxcr2-null mice and wild-type littermate controls. The RNA-seq dataset forms the bone marrow component of a multi-tissue study that also profiled articular cartilage and subchondral bone by microarray.
Links
Get the data
- GEO FTP directory ftp.ncbi.nlm.nih.gov/geo/series/GSE347nnn/GSE347515 ↗
download · from NCBI GEO
Where it is published
- GEO accession page ncbi.nlm.nih.gov/geo/query/acc.cgi?acc=GSE347515 ↗
landing page · from NCBI GEO
Documentation and papers
- PRJNA1530429 ncbi.nlm.nih.gov/bioproject/PRJNA1530429 ↗
project · from NCBI GEO
Topics
- Stated by source
- Expression profiling by high throughput sequencing · Mus musculus
- From keywords
- Life Sciences
- Inferred from text
- RNA sequencing 65%
Provenance · 1 source records, 8 field assertions
| Source | Key | Last seen | Raw |
|---|---|---|---|
| NCBI GEO | GSE347515 | 15 d ago | JSON v1 |
| Field | Assertion | Extractor | Evidence |
|---|---|---|---|
| access_level | source · NCBI GEO | connector:ncbi_geo@1.0.0 | |
| concepts[field].local:field:life-sciences | mapping · NCBI GEO | connector:ncbi_geo@1.0.0 | |
| concepts[method].geo_series_type:expression-profiling-by-high-throughput-sequencing | source · NCBI GEO | connector:ncbi_geo@1.0.0 | /gdstype |
| concepts[modality].local:modality:rna-seq | enrichment · NCBI GEO | keyword-concept-rules@1.0.0 | title+description (65%) |
| concepts[organism].NCBITaxon:10090 | source · NCBI GEO | connector:ncbi_geo@1.0.0 | /taxon |
| description | source · NCBI GEO | connector:ncbi_geo@1.0.0 | /summary |
| publication_date | source · NCBI GEO | connector:ncbi_geo@1.0.0 | |
| title | source · NCBI GEO | connector:ncbi_geo@1.0.0 | /title |