Genome-wide expression changes induced by heat shock response in indigenous cattle ( Bos indicus)

It compromises the immune defense mechanisms and metabolic functions there by increasing the risk of diseases and poor productive performances. Compared to environmentally sensitive Bos taurus breeds, Bos indicus cattle breeds thrive better in tropical climates due to their heat tolerance; however, accelerating climate extremes now threaten even these resilient animals.

To explore their underlying coping mechanisms, the present study mapped genome-wide gene expression changes in the B. indicus Hariana breed during heat exposure. The results indicated activation of set of gene clusters activated under stress. The functional characterization indicated molecular networks that suggested potential heat tolerance mechanisms.