Omics · study · 2026
Body weight at weaning is the main predictor for diabetic phenotype in male TallyHo/JngJ mice
Listed in NCBI GEO
TallyHo/JngJ (TallyHo) mice are a polygenic mouse model for type 2 diabetes (T2D), first described in 2001 and characterized by obesity due to an increased mass of fat pads.
Description
We aimed to discover whether environmental condition(s) during early life time or epigenetic factors across generations could be responsible for the varying penetrance of the metabolic phenotype of male and female TallyHo mice. Therefore, we set up the subsequent study in which we analyzed parameters of glucose homeostasis and environmental factors of individual TallyHo mice rather than relying on group averages.
Links
Get the data
- GEO FTP directory ftp.ncbi.nlm.nih.gov/geo/series/GSE235nnn/GSE235792 ↗
download · from NCBI GEO
Where it is published
- GEO accession page ncbi.nlm.nih.gov/geo/query/acc.cgi?acc=GSE235792 ↗
landing page · from NCBI GEO
Documentation and papers
- PRJNA987632 ncbi.nlm.nih.gov/bioproject/PRJNA987632 ↗
project · from NCBI GEO
Topics
- Stated by source
- Expression profiling by high throughput sequencing · Mus musculus
- From keywords
- Life Sciences
Provenance · 1 source records, 7 field assertions
| Source | Key | Last seen | Raw |
|---|---|---|---|
| NCBI GEO | GSE235792 | 13 d ago | JSON v1 |
| Field | Assertion | Extractor | Evidence |
|---|---|---|---|
| access_level | source · NCBI GEO | connector:ncbi_geo@1.0.0 | |
| concepts[field].local:field:life-sciences | mapping · NCBI GEO | connector:ncbi_geo@1.0.0 | |
| concepts[method].geo_series_type:expression-profiling-by-high-throughput-sequencing | source · NCBI GEO | connector:ncbi_geo@1.0.0 | /gdstype |
| concepts[organism].NCBITaxon:10090 | source · NCBI GEO | connector:ncbi_geo@1.0.0 | /taxon |
| description | source · NCBI GEO | connector:ncbi_geo@1.0.0 | /summary |
| publication_date | source · NCBI GEO | connector:ncbi_geo@1.0.0 | |
| title | source · NCBI GEO | connector:ncbi_geo@1.0.0 | /title |