Research Advances in Neonatal Hemolytic Disease Caused by Unexpected Antibodies.

In addition, non blood group incompatibility factors between mothers and fetus, such as immunoglobulin drugs, maternal autoantibodies, and breast milk Abs can also cause HDFN. These types of HDFN are characterized by low incidence but latency, rapid disease progression, and the risk of disability or death.

Therefore, the review of the diagnosis and treatment of these types of HDFN is of great importance to obstetrical department. Currently, laboratory diagnosis of these types of HDFN mainly includes testing of pregnant women and testing of fetuses. Treatment methods include phototherapy, drug therapy, and blood therapy.