Table · dataset · 2026
Dataset for 'GBA1 deficiency differentially affects endolysosomal trafficking in neurons versus astrocytes'
Listed in Teesside University Research Data Repository
This dataset contains the raw data supporting all main and supplementary figures in the manuscript 'GBA1 deficiency differentially affects endolysosomal trafficking in neurons versus astrocytes' intended for submission to Neurobiology of Disease.
Description
The dataset includes analyses of endolysosomal trafficking and alpha-synuclein pathology in dopaminergic neurons and astrocytes differentiated from iPSCs generated from an individual with Parkinson's disease carrying the GBA1 pathogenic variant GBA1 c.115+1 G>A, also known as IVS2+1 G>A, and an unrelated sex- and age-matched healthy control.
The dataset also includes transcriptomic analysis of GBA1 deficient iPSC-neurons and astrocytes compared to GBA1-wildtype iPSC-neurons and astrocytes.
Links
Where it is published
- DOI doi.org/10.17632/fgswr9ctcr.1 ↗
DOI / persistent id · from researchdata tees ac uk
Catalogue records · 1
- OAI-PMH record data.mendeley.com/oai?verb=GetRecord&metadataPrefix=oai_dc&identifier=oai%3Adata… ↗
metadata API · from researchdata tees ac uk
Topics
- From keywords
- Astronomy & Astrophysics · Earth & Environmental Science · Engineering · Humanities · Life Sciences · Social Science
- Inferred from text
- Biochemistry and cell biology 72% · Disease 75%
Provenance · 1 source records, 12 field assertions
| Source | Key | Last seen | Raw |
|---|---|---|---|
| Teesside University Research Data Repository | oai:data.mendeley.com/fgswr9ctcr.1 | 12 d ago | JSON v1 |
| Field | Assertion | Extractor | Evidence |
|---|---|---|---|
| concepts[disease].local:disease:disease | enrichment · researchdata tees ac uk | keyword-concept-rules@1.0.0 | title+description (75%) |
| concepts[field].anzsrc:group:3101 | enrichment · researchdata tees ac uk | taxonomy-embedding@1.0.0 | title+keywords+description (72%) |
| concepts[field].local:field:astronomy | mapping · researchdata tees ac uk | connector:researchdata_tees_ac_uk@1.0.0 | |
| concepts[field].local:field:earth-environmental | mapping · researchdata tees ac uk | connector:researchdata_tees_ac_uk@1.0.0 | |
| concepts[field].local:field:engineering | mapping · researchdata tees ac uk | connector:researchdata_tees_ac_uk@1.0.0 | |
| concepts[field].local:field:humanities | mapping · researchdata tees ac uk | connector:researchdata_tees_ac_uk@1.0.0 | |
| concepts[field].local:field:life-sciences | mapping · researchdata tees ac uk | connector:researchdata_tees_ac_uk@1.0.0 | |
| concepts[field].local:field:social-science | mapping · researchdata tees ac uk | connector:researchdata_tees_ac_uk@1.0.0 | |
| description | source · researchdata tees ac uk | connector:researchdata_tees_ac_uk@1.0.0 | /metadata/dc/description |
| license_text | source · researchdata tees ac uk | connector:researchdata_tees_ac_uk@1.0.0 | |
| publication_date | source · researchdata tees ac uk | connector:researchdata_tees_ac_uk@1.0.0 | |
| title | source · researchdata tees ac uk | connector:researchdata_tees_ac_uk@1.0.0 | /metadata/dc/title |