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Excel · study · 2026

Transcriptomics profiling of gonadal white adipose tissue (gWAT) of Floxed Control (WT), and Gα12 knockout mice (Gα12 KO) mice fed a normal chow diet (NCD) or high-fat diet (HFD)

Listed in NCBI GEO

The therapeutic relevance of GPCR-targeting drugs has expanded, yet the function of Gα12/13 in adipose tissue remain incompletely understood.

Description

This study investigated the metabolic roles of Gα12/13 in adipocytes under conditions of diet-induced obesity. Transcriptomic analysis was performed on gonadal white adipose tissue collected from Floxed Control (WT) and Gα12 knockout mice (Gα12) after 16 weeks of high-fat diet feeding.

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Life Sciences
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Biochemistry and cell biology 69%
Provenance · 1 source records, 8 field assertions
SourceKeyLast seenRaw
NCBI GEOGSE33081115 d agoJSON v1
FieldAssertionExtractorEvidence
access_levelsource · NCBI GEOconnector:ncbi_geo@1.0.0
concepts[field].anzsrc:group:3101enrichment · NCBI GEOtaxonomy-embedding@1.1.0title+keywords+description (69%)
concepts[field].local:field:life-sciencesmapping · NCBI GEOconnector:ncbi_geo@1.0.0
concepts[method].geo_series_type:expression-profiling-by-high-throughput-sequencingsource · NCBI GEOconnector:ncbi_geo@1.0.0/gdstype
concepts[organism].NCBITaxon:10090source · NCBI GEOconnector:ncbi_geo@1.0.0/taxon
descriptionsource · NCBI GEOconnector:ncbi_geo@1.0.0/summary
publication_datesource · NCBI GEOconnector:ncbi_geo@1.0.0
titlesource · NCBI GEOconnector:ncbi_geo@1.0.0/title