Omics · study · 2026
Gene expression profile at single cell level of calvarial bone defect in diabetes
Listed in NCBI GEO
The diabetic SD rat model was established by intraperitoneal injection of streptozotocin (STZ) 7 weeks prior to surgery.
Description
A 5 mm-diameter calvarial defect was created in both diabetic and control rats to investigate the impact of diabetes on bone healing. Before suturing, the defect was filled with a gelatin sponge.
Rats were euthanized via carbon dioxide inhalation at 3 days post-surgery to retrieve the hematoma-adsorbed gelatin sponges. Cells from the sponges of both groups were collected for single-cell transcriptomic analysis.
Links
Get the data
- GEO FTP directory ftp.ncbi.nlm.nih.gov/geo/series/GSE316nnn/GSE316916 ↗
download · from NCBI GEO
Where it is published
- GEO accession page ncbi.nlm.nih.gov/geo/query/acc.cgi?acc=GSE316916 ↗
landing page · from NCBI GEO
Documentation and papers
- PRJNA1404411 ncbi.nlm.nih.gov/bioproject/PRJNA1404411 ↗
project · from NCBI GEO
Topics
- Stated by source
- Expression profiling by high throughput sequencing · Rattus norvegicus
- From keywords
- Life Sciences
Provenance · 1 source records, 7 field assertions
| Source | Key | Last seen | Raw |
|---|---|---|---|
| NCBI GEO | GSE316916 | 15 d ago | JSON v1 |
| Field | Assertion | Extractor | Evidence |
|---|---|---|---|
| access_level | source · NCBI GEO | connector:ncbi_geo@1.0.0 | |
| concepts[field].local:field:life-sciences | mapping · NCBI GEO | connector:ncbi_geo@1.0.0 | |
| concepts[method].geo_series_type:expression-profiling-by-high-throughput-sequencing | source · NCBI GEO | connector:ncbi_geo@1.0.0 | /gdstype |
| concepts[organism].NCBITaxon:10116 | source · NCBI GEO | connector:ncbi_geo@1.0.0 | /taxon |
| description | source · NCBI GEO | connector:ncbi_geo@1.0.0 | /summary |
| publication_date | source · NCBI GEO | connector:ncbi_geo@1.0.0 | |
| title | source · NCBI GEO | connector:ncbi_geo@1.0.0 | /title |