Omics · study · 2026
SMC1A is required for fate determinations of human spermatogonial stem cells and male fertility by interacting with YBX1 and stabilizing HMGA2 mRNA via an m5C modification_YBX1_siRNA
Listed in NCBI GEO
Spermatogonial stem cells (SSCs) are required for initiating and maintaining normal spermatogenesis, and notably, they have significant applications in both reproductive and regenerative medicine owing to their great plasticity with de-differentiation and trans-differentiation potentials.
Description
Nevertheless, molecular mechanisms regulating human SSC fate determinations and male fertility remain elusive.
Links
Get the data
- GEO FTP directory ftp.ncbi.nlm.nih.gov/geo/series/GSE336nnn/GSE336268 ↗
download · from NCBI GEO
Where it is published
- GEO accession page ncbi.nlm.nih.gov/geo/query/acc.cgi?acc=GSE336268 ↗
landing page · from NCBI GEO
Documentation and papers
- PRJNA1481194 ncbi.nlm.nih.gov/bioproject/PRJNA1481194 ↗
project · from NCBI GEO
- PubMed 42745033 pubmed.ncbi.nlm.nih.gov/42745033 ↗
publication · from NCBI GEO
Topics
- Stated by source
- Expression profiling by high throughput sequencing · Homo sapiens
- From keywords
- Life Sciences
Provenance · 1 source records, 7 field assertions
| Source | Key | Last seen | Raw |
|---|---|---|---|
| NCBI GEO | GSE336268 | 7 d ago | JSON v1 |
| Field | Assertion | Extractor | Evidence |
|---|---|---|---|
| access_level | source · NCBI GEO | connector:ncbi_geo@1.0.0 | |
| concepts[field].local:field:life-sciences | mapping · NCBI GEO | connector:ncbi_geo@1.0.0 | |
| concepts[method].geo_series_type:expression-profiling-by-high-throughput-sequencing | source · NCBI GEO | connector:ncbi_geo@1.0.0 | /gdstype |
| concepts[organism].NCBITaxon:9606 | source · NCBI GEO | connector:ncbi_geo@1.0.0 | /taxon |
| description | source · NCBI GEO | connector:ncbi_geo@1.0.0 | /summary |
| publication_date | source · NCBI GEO | connector:ncbi_geo@1.0.0 | |
| title | source · NCBI GEO | connector:ncbi_geo@1.0.0 | /title |