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Omics · study · 2026

RNA-seq analysis of Srsf3 conditional knockout mouse breast tumor and liver tumor tissues

Listed in NCBI GEO

SRSF3 is an important splicing factor and was identified as a protooncogene of which increased expression leads to cell immortalization, transformation, and tumorigenesis.

Description

We generated Srsf3 conditional knock-out (KO) mice separately in breast or liver tissues to investigate how SRSF3 contribute to the development of different mammalian tumors,

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Expression profiling by high throughput sequencing · Mus musculus
From keywords
Life Sciences
Inferred from text
Cancer 65% · RNA sequencing 65%
Provenance · 1 source records, 9 field assertions
SourceKeyLast seenRaw
NCBI GEOGSE27601115 d agoJSON v1
FieldAssertionExtractorEvidence
access_levelsource · NCBI GEOconnector:ncbi_geo@1.0.0
concepts[disease].local:disease:cancerenrichment · NCBI GEOkeyword-concept-rules@1.0.0title+description (65%)
concepts[field].local:field:life-sciencesmapping · NCBI GEOconnector:ncbi_geo@1.0.0
concepts[method].geo_series_type:expression-profiling-by-high-throughput-sequencingsource · NCBI GEOconnector:ncbi_geo@1.0.0/gdstype
concepts[modality].local:modality:rna-seqenrichment · NCBI GEOkeyword-concept-rules@1.0.0title+description (65%)
concepts[organism].NCBITaxon:10090source · NCBI GEOconnector:ncbi_geo@1.0.0/taxon
descriptionsource · NCBI GEOconnector:ncbi_geo@1.0.0/summary
publication_datesource · NCBI GEOconnector:ncbi_geo@1.0.0
titlesource · NCBI GEOconnector:ncbi_geo@1.0.0/title