Excel · study · 2026
The gene expression of primitive macrophage derived from human induced pluripotent stem cells treated by PNU282987
Listed in NCBI GEO
Microglia are immune cells in the brain originating from primitive macrophages, which developed in the yolk sac during embryonic development.
Description
We have previously found that stimulation of the nicotinic acetylcholine receptor α7 subtype (α7 nAChR) in rodent microglia promotes the phagocytosis. In this study, we performed a comprehensive gene expression analysis of human induced pluripotent stem cell-derived primitive macrophages treated with a full agonist of α7 nAChR, PNU282987, to evaluate gene expression changes human microglia model system.
Links
Get the data
- GEO FTP directory ftp.ncbi.nlm.nih.gov/geo/series/GSE295nnn/GSE295886 ↗
download · from NCBI GEO
Where it is published
- GEO accession page ncbi.nlm.nih.gov/geo/query/acc.cgi?acc=GSE295886 ↗
landing page · from NCBI GEO
Documentation and papers
- PRJNA1256728 ncbi.nlm.nih.gov/bioproject/PRJNA1256728 ↗
project · from NCBI GEO
Topics
- Stated by source
- Expression profiling by high throughput sequencing · Homo sapiens
- From keywords
- Life Sciences
Provenance · 1 source records, 7 field assertions
| Source | Key | Last seen | Raw |
|---|---|---|---|
| NCBI GEO | GSE295886 | 13 d ago | JSON v1 |
| Field | Assertion | Extractor | Evidence |
|---|---|---|---|
| access_level | source · NCBI GEO | connector:ncbi_geo@1.0.0 | |
| concepts[field].local:field:life-sciences | mapping · NCBI GEO | connector:ncbi_geo@1.0.0 | |
| concepts[method].geo_series_type:expression-profiling-by-high-throughput-sequencing | source · NCBI GEO | connector:ncbi_geo@1.0.0 | /gdstype |
| concepts[organism].NCBITaxon:9606 | source · NCBI GEO | connector:ncbi_geo@1.0.0 | /taxon |
| description | source · NCBI GEO | connector:ncbi_geo@1.0.0 | /summary |
| publication_date | source · NCBI GEO | connector:ncbi_geo@1.0.0 | |
| title | source · NCBI GEO | connector:ncbi_geo@1.0.0 | /title |