Data · dataset · 2026
Data from: A six-hour time series of the acute effects of ingested cannabis intoxication on a battery of cognitive-motor tasks
Listed in Borealis
The psychoactive component of cannabis, Δ9-tetrahydrocannabinol (THC), is known to alter cognitive-motor function; however, despite the high prevalence of cannabis use globally, the time course of the effects of ingesting THC is unclear.
Description
To allow future studies to accurately time their assessment of the impacts of cannabis on behaviour, this study aimed to establish a detailed time series of subjective intoxication and cognitive-motor performance following THC ingestion.
Fifteen infrequent cannabis users (8 females; 29.4 ± 8.1 years) completed a testing battery before (baseline) and at 11 timepoints (0-6h) after ingesting two 5-mg THC capsules. Subjective drug effects and cardiovascular measures were recorded, and cognitive-motor function was measured via performance on simple reaction time, go/no-go reaction time, and Corsi block tapping tasks. Linear mixed-effects models were used to determine if subjective and objective measures changed during the time series.
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Compared to baseline, participants reported significant subjective drug effects 1-6h post-ingestion. Heart rate was elevated from 3-6h, whereas blood pressure was elevated at timepoints between 1-4h. Individuals demonstrated a robust increase of simple reaction time from 1-6h, reduced go/no-go accuracy between 1.5-6h, and impaired Corsi blocking tapping performance between 1-5h.
Overall, the ideal window to test the cognitive-motor effects of cannabis intoxication appears at 3-4h post-THC ingestion, with a marked perception of feeling high between 2-5h.
Links
Where it is published
- Dataverse dataset page borealisdata.ca/dataset.xhtml?persistentId=doi%3A10.5683%2FSP4%2FCHLU6F ↗
landing page · from borealisdata ca
- DOI doi.org/10.5683/sp4/chlu6f ↗
DOI / persistent id · from borealisdata ca
Catalogue records · 1
- Dataverse API borealisdata.ca/api/datasets/:persistentId/?persistentId=doi%3A10.5683%2FSP4%2… ↗
metadata API · from borealisdata ca
Topics
- Stated by source
- Medicine, Health and Life Sciences
- From keywords
- Life Sciences · Medicine & Health
- Inferred from text
- Heart 75%
Provenance · 1 source records, 10 field assertions
| Source | Key | Last seen | Raw |
|---|---|---|---|
| Borealis | doi:10.5683/SP4/CHLU6F | 13 d ago | JSON v1 |
| Field | Assertion | Extractor | Evidence |
|---|---|---|---|
| concepts[anatomy].local:anatomy:heart | enrichment · borealisdata ca | keyword-concept-rules@1.0.0 | title+description (75%) |
| concepts[field].dataverse_subject:medicine-health-and-life-sciences | source · borealisdata ca | connector:borealisdata_ca@1.0.0 | /subjects |
| concepts[field].local:field:life-sciences | mapping · borealisdata ca | connector:borealisdata_ca@1.0.0 | /subjects |
| concepts[field].local:field:medicine-health | mapping · borealisdata ca | connector:borealisdata_ca@1.0.0 | /subjects |
| created_date | source · borealisdata ca | connector:borealisdata_ca@1.0.0 | |
| description | source · borealisdata ca | connector:borealisdata_ca@1.0.0 | /description |
| publication_date | source · borealisdata ca | connector:borealisdata_ca@1.0.0 | |
| title | source · borealisdata ca | connector:borealisdata_ca@1.0.0 | /name |
| updated_date | source · borealisdata ca | connector:borealisdata_ca@1.0.0 | |
| version_label | source · borealisdata ca | connector:borealisdata_ca@1.0.0 |