Table · dataset · 2026
Supplementary file 1_Utahmycin C, a new glycosylated derivative of a rare azaanthraquinone produced by Streptomyces sp. YD248.docx
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<p>Chemical investigation of Streptomyces sp.
Description
YD248 led to the isolation of utahmycin C (1), a new glycosylated member of the rare bacterial 1,3-dimethyl-2-azaanthraquinone family. Its structure was established by NMR spectroscopy and high-resolution mass spectrometry, revealing a β-D-glucuronic acid substituent attached to the azaanthraquinone core.
Unusual long-range <sup>5</sup>J HMBC correlations prompted validation by density functional theory (DFT) through NMR chemical shift calculations, which showed excellent agreement with the experimental data. Bioinformatics analysis identified a biosynthetic gene cluster (BGC) homologous to the reported Erd gene cluster associated with utahmycin A biosynthesis. This study expands the structural diversity of bacterial azaanthraquinones.</p>
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Where it is published
- DOI doi.org/10.3389/fmicb.2026.1921234.s001 ↗
DOI / persistent id · from figshare com
Catalogue records · 1
- OAI-PMH record api.figshare.com/v2/oai?verb=GetRecord&metadataPrefix=oai_dc&identifier=oai%3Af… ↗
metadata API · from figshare com
Topics
- From keywords
- Astronomy & Astrophysics · Chemistry · Computer Science & AI · Earth & Environmental Science · Economics & Finance · Engineering · Humanities · Life Sciences · Medicine & Health · Microbiology · Ocean & Atmospheric Science · Social Science
- Inferred from text
- Density functional theory 75% · Mass spectrometry 75%
Provenance · 1 source records, 19 field assertions
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