Micro-sized nanoaggregates: Spray-drying-assisted fabrication and applications

Rearranging nanoparticles to form micro-sized nanoaggregates (MNAs) with increased size, ordered structure, as well as controllable size, shape, and morphology is a crucial step in various fields of science and technology to maintain the unique characteristics of nanoparticles while obtaining greatly enhanced or new performance at the microscale.

The structure of MNAs prominently affects their functionality, which is determined by the arrangement of nanoparticles and the interaction between primary particles. Several methods have been proposed to prepare the MNAs, in which spray-drying technology stands out considering the feasibility, scalability for industry, cost, and efficiency. Forced assembly of nanoparticles through spray-drying under tunable process parameters yields diverse physical properties and structural arrangements of nanoparticles of the MNAs, they therefore exhibit enormous potential in a wide range of application fields.