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Data · dataset · 2026

<p>Immune-mediated disease and psychiatric disorders correlated factors models and correlations between immune and psychiatric factors.</p>

Listed in ZivaHub and Deakin Research Online and DMU Figshare — shown once because both records carry DOI 10.1371/journal.pgen.1012328.g001

<p><b>A)</b> Immune-mediated diseases path diagram with standardized estimates for the correlated factors model used in genomic structural equation modelling (genomic SEM) with four factors of immune-mediated diseases.

Description

Latent variables are represented as circles. The genetic component of each phenotype is represented with a circle because the genetic component is a latent variable that is not directly measured but is inferred using linkage disequilibrium score regression (LDSC).

Single-headed arrows are factor loadings; double-headed arrows connecting back to the same origin are variances; and double-headed arrows connecting two variables are correlations. Paths labeled 1 are fixed to 1; all estimates are given next to the path with standard errors in parentheses. Disease abbreviations are defined in <a href="plosgenetics.org/article/info:doi/10.1371/journal.pgen.1012328#pgen.1012328.t001" target="_blank">Table 1</a>. <b>B)</b> Psychiatric disorders path diagram.

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Disorder abbreviations are defined in <a href="plosgenetics.org/article/info:doi/10.1371/journal.pgen.1012328#pgen.1012328.t001" target="_blank">Table 1</a>. <b>C)</b> Genetic correlations between factors of immune-mediated diseases and factors of psychiatric disorders. IMMUNE, autoimmune diseases; CEL, celiac disease; MIXED, mixed immune pattern diseases; INFLAMM, inflammatory diseases; COMP, compulsive disorders; SB, schizophrenia/bipolar; NEURO, neurodevelopmental disorders; INT, internalizing disorders; SUD, substance use disorders.</p>

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Catalogue records · 1

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Inferred from text
Disease 75% · Tabular 65%
Provenance · 3 source records, 31 field assertions
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FieldAssertionExtractorEvidence
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