Data for: Detection of cytokines (IL-1α and IL-2) and oxidative stress markers in hepatitis B envelope antigen-positive and -negative chronic hepatitis B patients: Molecular and biochemical study

One of the conclusions of the present study is that qRT-PCR is a sensitive, specific, and reproducible approach for detecting and quantifying HBV-DNA in clinical serum samples; it can also serve as an essential supplementary tool in clinical settings, especially for establishing viremia levels (follow up before and after treatment) in HBeAg-positive or -negative patients with CHB.

Our study also demonstrated that production of the lipid peroxidation marker, MDA, is significantly reduced in patients infected with HBV. Further, IL-1α and IL-2 levels revealed information about the HBV infection status and may be used as a parameter of hepatic inflammation as the IL-2 levels were significantly lower in HBeAg-positive patients than in HBeAg-negative patients.