Comparative transcriptomic analysis of lettuce under cadmium and selenium nanoparticle treatments

This study investigated the role of biosynthesized selenium nanoparticles (SeNPs) derived from Chlorella sorokiniana SZ2-1 in alleviating cadmium (Cd) toxicity in Lettuce (Lactuca sativa L. cv.‘Red oak-leaf’) under hydroponic conditions.The research focused on evaluating the effects of SeNPs on Cd uptake, translocation, subcellular distribution, selenium speciation, and stress-responsive transcriptional regulation. Lettuce seedlings were exposed to Cd alone or in combination with different concentrations of SeNPs.

Physiological, biochemical, ionomic, transcriptomic, and metabolomic analyses were conducted to elucidate the detoxification mechanisms induced by SeNPs.