Omics · study · 2026
Genome-wide methylation analysis identifies epigenetic differences in human ILC2s from healthy, atopic, and asthmatic young donors
Listed in NCBI GEO
DNA methylation of CpG motifs represents a stable epigenetic mark that critically influences the differentiation, stability and function of immune cell populations.
Description
Identifying differentially methylated regions within immune cell lineages contributes to their phenotypic and functional characterization, leading to a better understanding of lineage-specific transcriptional regulation. In this study, we performed a genome-wide methylation analysis of type 2 innate lymphoid cells (ILC2) from healthy (HE), atopic (AT) and asthmatic (AS) young individuals, to investigate inflammation-driven epigenetic changes during human development.
Links
Get the data
- GEO FTP directory ftp.ncbi.nlm.nih.gov/geo/series/GSE314nnn/GSE314735 ↗
download · from NCBI GEO
Where it is published
- GEO accession page ncbi.nlm.nih.gov/geo/query/acc.cgi?acc=GSE314735 ↗
landing page · from NCBI GEO
Documentation and papers
- PRJNA1392513 ncbi.nlm.nih.gov/bioproject/PRJNA1392513 ↗
project · from NCBI GEO
Topics
- Stated by source
- Homo sapiens · Methylation profiling by high throughput sequencing
- From keywords
- Life Sciences
- Inferred from text
- Epigenetics 79%
Provenance · 1 source records, 8 field assertions
| Source | Key | Last seen | Raw |
|---|---|---|---|
| NCBI GEO | GSE314735 | 14 d ago | JSON v1 |
| Field | Assertion | Extractor | Evidence |
|---|---|---|---|
| access_level | source · NCBI GEO | connector:ncbi_geo@1.0.0 | |
| concepts[field].anzsrc:field:310504 | enrichment · NCBI GEO | taxonomy-embedding@1.1.0 | title+keywords+description (79%) |
| concepts[field].local:field:life-sciences | mapping · NCBI GEO | connector:ncbi_geo@1.0.0 | |
| concepts[method].geo_series_type:methylation-profiling-by-high-throughput-sequencing | source · NCBI GEO | connector:ncbi_geo@1.0.0 | /gdstype |
| concepts[organism].NCBITaxon:9606 | source · NCBI GEO | connector:ncbi_geo@1.0.0 | /taxon |
| description | source · NCBI GEO | connector:ncbi_geo@1.0.0 | /summary |
| publication_date | source · NCBI GEO | connector:ncbi_geo@1.0.0 | |
| title | source · NCBI GEO | connector:ncbi_geo@1.0.0 | /title |