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Text · dataset · 2026

Data for: "Proof-of-concept trial of electronic monitoring devices for adolescents living with HIV in Zimbabwe"

Listed in LSHTM Data Compass

The VITALITY randomised controlled trial investigated the effectiveness of vitamin D and calcium supplementation on bone density in adolescents living with HIV.

Description

Nested within VITALITY, this pilot trial investigated the effectiveness of electronic monitoring devices (EMDs) on adherence to vitamin D supplementation in Harare, Zimbabwe. 169 adolescents living with HIV were randomised to receive an EMD (N=97) or no EMD (n=72) for 24 weeks. 84 of the adolescents were taking vitamin D supplements (N=50 with EMD, N=34 without EMD).

The pilot trial compared 25OHD levels in blood between the EMD and non-EMD participants receiving vitamin D supplements after 24 weeks as a marker of adherence. This record contains two datasets, an R script, Stata do file, and accompanying documentation: (1) The ‘EMD_minimal_deidentified’ dataset contains records on 97 participants who were randomly allocated to receive an electronic monitoring device and 72 participants who were randomly allocated to not receive one.

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It can be analysed with the Stata do file “Minimal dataset.do”, which replicates the pilot trial analysis of adherence and vitamin D level by EMD arm, among those who were receiving vitamin D supplement in the parent VITALITY trial. (2) The ‘ml_preprocessed_for_R’ dataset contains records on 97 participants who received an electronic monitoring device. It can be analysed with the R script “clustering_deidentified.R, which reproduces the unsupervised machine learning techniques for exploratory analysis of patterns of EMD use over 24 weeks, using k-means clustering, k-medoids clustering, hierarchical agglomerative clustering and Gaussian mixture model.

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Inferred from text
Nutrition and dietetics 69%
Provenance · 1 source records, 11 field assertions
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