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Data · dataset · 2026

Dragon

Listed in LSHTM Data Compass

Resource-efficient sequence alignment against millions of prokaryotic genomes using graph-based compressed indexing.

Description

Dragon aligns query sequences (genes, plasmids, long reads) against millions of prokaryotic genomes while using dramatically less disk and RAM than existing tools. It achieves this by exploiting the massive sequence redundancy among related genomes through three key innovations: (1) Coloured compacted de Bruijn graph - shared sequence stored once across all genomes, (2) Run-length FM-index - compressed seed index proportional to BWT runs, not text length, and (3) Graph-aware colinear chaining - seed chaining that respects genome graph structure.

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Where it is published

Catalogue records · 1

Topics

Inferred from text
Sequence analysis 77% · Text 75%
Provenance · 1 source records, 10 field assertions
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