Table · dataset · 2026
<p>Minimal datasets for dose response study.</p>
Listed in figshare
<div><p>Botanical repellents provide a traditional means of personal protection, yet optimizing their formulations is increasingly required to address shifting mosquito feeding behaviors and mitigate disease transmission.
Description
The current study aimed to evaluate the repellent efficacy of essential oils and their binary combinations as complex matrices against <i>Anopheles arabiensis</i> bites<i>,</i> the major malaria vector in Ethiopia.
Essential oils were extracted from fresh parts of four ethnobotanically investigated medicinal plants in the Ghibe Valley, Ethiopia, namely <i>Croton macrostachyus</i>, <i>Echinops kebericho</i>, <i>Eucalyptus globulus,</i> and <i>Juniperus procera</i> using hydrodistillation. The chemical composition of the essential oils was analyzed by Gas Chromatography-Mass Spectrometry (GC-MS). Arm-in-cage bioassays using laboratory-reared mosquitoes and human volunteers determined the effective dosage and complete protection time of the essential oils at 10% and 20% concentrations.
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A total of 131 chemical constituents were identified across the four analyzed essential oils. The <i>C. macrostachyus</i> leaf and seed oils provided a significantly longer protection time (<i>p</i> < 0.001), reaching 180 minutes with a mean percentage repellency of 85% to 100%. The essential oil of <i>J. procera</i> blended with <i>C. macrostachyus</i> or <i>E. kebericho</i> exhibited significant synergistic repellency (<i>p</i> < 0.001).
The protection duration demonstrating by <i>C. macrostachyus</i> oil underscores their potential to meet the regulatory performance standards for natural insect repellents. Future investigations should include larger sample sizes, dermal toxicity assessments and field validation to fully support the commercialization of these essential oils.</p></div>
Links
Where it is published
- DOI doi.org/10.1371/journal.pone.0358040.s005 ↗
DOI / persistent id · from figshare com
Catalogue records · 1
- OAI-PMH record api.figshare.com/v2/oai?verb=GetRecord&metadataPrefix=oai_dc&identifier=oai%3Af… ↗
metadata API · from figshare com
Topics
- From keywords
- Astronomy & Astrophysics · Chemistry · Computer Science & AI · Earth & Environmental Science · Ecology · Economics & Finance · Engineering · Humanities · Life Sciences · Medicine & Health · Ocean & Atmospheric Science · Social Science · Sociology
- Inferred from text
- Disease 75%
Provenance · 1 source records, 19 field assertions
| Source | Key | Last seen | Raw |
|---|---|---|---|
| figshare | oai:figshare.com:article/33810866 | 11 d ago | JSON v1 |
| Field | Assertion | Extractor | Evidence |
|---|---|---|---|
| access_level | source · figshare com | connector:figshare_com@1.0.0 | |
| concepts[disease].local:disease:disease | enrichment · figshare com | keyword-concept-rules@1.0.0 | title+description (75%) |
| concepts[field].anzsrc:group:3103 | mapping · figshare com | vocabulary-mapper@1.0.0 | keywords['Ecology'] |
| concepts[field].anzsrc:group:4410 | mapping · figshare com | vocabulary-mapper@1.0.0 | keywords['Sociology'] |
| concepts[field].local:field:astronomy | mapping · figshare com | connector:figshare_com@1.0.0 | |
| concepts[field].local:field:chemistry | mapping · figshare com | connector:figshare_com@1.0.0 | |
| concepts[field].local:field:computer-science-ai | mapping · figshare com | connector:figshare_com@1.0.0 | |
| concepts[field].local:field:earth-environmental | mapping · figshare com | connector:figshare_com@1.0.0 | |
| concepts[field].local:field:economics-finance | mapping · figshare com | connector:figshare_com@1.0.0 | |
| concepts[field].local:field:engineering | mapping · figshare com | connector:figshare_com@1.0.0 | |
| concepts[field].local:field:humanities | mapping · figshare com | connector:figshare_com@1.0.0 | |
| concepts[field].local:field:life-sciences | mapping · figshare com | connector:figshare_com@1.0.0 | |
| concepts[field].local:field:medicine-health | mapping · figshare com | connector:figshare_com@1.0.0 | |
| concepts[field].local:field:ocean-atmospheric | mapping · figshare com | connector:figshare_com@1.0.0 | |
| concepts[field].local:field:social-science | mapping · figshare com | connector:figshare_com@1.0.0 | |
| description | source · figshare com | connector:figshare_com@1.0.0 | /metadata/dc/description |
| license | source · figshare com | connector:figshare_com@1.0.0 | /metadata/dc/rights |
| publication_date | source · figshare com | connector:figshare_com@1.0.0 | |
| title | source · figshare com | connector:figshare_com@1.0.0 | /metadata/dc/title |