Data · collection · 2019
X-ray diffraction data of GerE
Listed in NASA Earthdata CMR
In cold and harsh environments such as glaciers and sediments in ice cores, microbes can survive by forming spores.
Description
Spores are composed of a thick coat protein, which protects against external factors such as heat-shock, high salinity, and nutrient deficiency. GerE is a key transcription factor involved in spore coat protein expression in the mother cell during sporulation.
GerE regulates transcription during the late sporulation stage by directly binding to the promoter of cotB gene. Here, we report the crystal structure of PaGerE at 2.09 ? resolution from Paenisporosarcina sp. TG-14, which was isolated from the Taylor glacier.
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The PaGerE structure is composed of four α-helices and adopts a helix-turn-helix architecture with 68 amino acid residues. Based on our DNA binding analysis, the PaGerE binds to the promoter region of CotB to affect protein expression. Additionally, our structural comparison studies suggest that DNA binding by PaGerE causes a conformational change in the α4-helix region, which may strongly induce dimerization of PaGerE.
Links
Documentation and papers
- PROJECT HOME PAGE kpdc.kopri.re.kr ↗
project · from NASA CMR
Catalogue records · 2
- CMR record cmr.earthdata.nasa.gov/search/concepts/C2244301233-AMD_KOPRI.html ↗
catalogue entry · from NASA CMR
- CMR UMM-JSON cmr.earthdata.nasa.gov/search/concepts/C2244301233-AMD_KOPRI.umm_json ↗
metadata API · from NASA CMR
Topics
- Stated by source
- Community Dynamics · NOT APPLICABLE · NOT APPLICABLE
Provenance · 1 source records, 12 field assertions
| Source | Key | Last seen | Raw |
|---|---|---|---|
| NASA Earthdata CMR | C2244301233-AMD_KOPRI | 15 d ago | JSON v1 |
| Field | Assertion | Extractor | Evidence |
|---|---|---|---|
| access_level | source · NASA CMR | connector:nasa_cmr@1.0.0 | |
| concepts[instrument].gcmd_instrument:not-applicable | source · NASA CMR | connector:nasa_cmr@1.0.0 | |
| concepts[measured_variable].gcmd:earth-science/biosphere/ecological-dynamics/community-dynamics | source · NASA CMR | connector:nasa_cmr@1.0.0 | |
| concepts[platform].gcmd_platform:not-applicable | source · NASA CMR | connector:nasa_cmr@1.0.0 | |
| created_date | source · NASA CMR | connector:nasa_cmr@1.0.0 | |
| description | source · NASA CMR | connector:nasa_cmr@1.0.0 | /umm/Abstract |
| publication_date | source · NASA CMR | connector:nasa_cmr@1.0.0 | |
| spatial | source · NASA CMR | connector:nasa_cmr@1.0.0 | /umm/SpatialExtent |
| temporal | source · NASA CMR | connector:nasa_cmr@1.0.0 | /umm/TemporalExtents |
| title | source · NASA CMR | connector:nasa_cmr@1.0.0 | /umm/EntryTitle |
| updated_date | source · NASA CMR | connector:nasa_cmr@1.0.0 | |
| version_label | source · NASA CMR | connector:nasa_cmr@1.0.0 |