Omics · study · 2026
Unraveling the Spatial Dynamics of Immune-Epithelial Interactions in the Intestinal Tract
Listed in NCBI GEO
Intetsinal epithelium is the frontline of the gut mucosal barrier and consists of diversified epithelia cells playing different rols in the host defense against invading microorgansiums.
Description
Here, we studied the Microfold (M) cells located in the different regions of the intestine and generated a blueprint of M cells, in particular their gene expression and matuation programs. M cells, under steady state and the stress of pathogen (Salmonella or Citrobactor) invasion, were shown to have distinct gene expression profiles, highlighting their roles in denfensing different pathogens.
Links
Get the data
- GEO FTP directory ftp.ncbi.nlm.nih.gov/geo/series/GSE243nnn/GSE243533 ↗
download · from NCBI GEO
Where it is published
- GEO accession page ncbi.nlm.nih.gov/geo/query/acc.cgi?acc=GSE243533 ↗
landing page · from NCBI GEO
Documentation and papers
- PRJNA1018873 ncbi.nlm.nih.gov/bioproject/PRJNA1018873 ↗
project · from NCBI GEO
- PubMed 42601474 pubmed.ncbi.nlm.nih.gov/42601474 ↗
publication · from NCBI GEO
Topics
- Stated by source
- Expression profiling by high throughput sequencing · Mus musculus
- From keywords
- Life Sciences
- Inferred from text
- Biochemistry and cell biology 68%
Provenance · 1 source records, 8 field assertions
| Source | Key | Last seen | Raw |
|---|---|---|---|
| NCBI GEO | GSE243533 | 12 d ago | JSON v1 |
| Field | Assertion | Extractor | Evidence |
|---|---|---|---|
| access_level | source · NCBI GEO | connector:ncbi_geo@1.0.0 | |
| concepts[field].anzsrc:group:3101 | enrichment · NCBI GEO | taxonomy-embedding@1.1.0 | title+keywords+description (68%) |
| concepts[field].local:field:life-sciences | mapping · NCBI GEO | connector:ncbi_geo@1.0.0 | |
| concepts[method].geo_series_type:expression-profiling-by-high-throughput-sequencing | source · NCBI GEO | connector:ncbi_geo@1.0.0 | /gdstype |
| concepts[organism].NCBITaxon:10090 | source · NCBI GEO | connector:ncbi_geo@1.0.0 | /taxon |
| description | source · NCBI GEO | connector:ncbi_geo@1.0.0 | /summary |
| publication_date | source · NCBI GEO | connector:ncbi_geo@1.0.0 | |
| title | source · NCBI GEO | connector:ncbi_geo@1.0.0 | /title |