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Omics · study · 2026

Arginase-1 dependent Insulin-like Growth Factor-1 from myofibroblasts and endothelial cells facilitates kidney tubular proliferation after ischemic injury

Listed in NCBI GEO

Following acute kidney injury, successful regeneration of tubular epithelium is essential to restore normal kidney function.

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We have previously reported that alternatively activated (Arg1+) macrophages in the outer medulla promote tubular proliferation following ischemic injury, however the specific growth factor(s) mediating this effect remained unidentified.

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Life Sciences
Provenance · 1 source records, 7 field assertions
SourceKeyLast seenRaw
NCBI GEOGSE30424515 d agoJSON v1
FieldAssertionExtractorEvidence
access_levelsource · NCBI GEOconnector:ncbi_geo@1.0.0
concepts[field].local:field:life-sciencesmapping · NCBI GEOconnector:ncbi_geo@1.0.0
concepts[method].geo_series_type:expression-profiling-by-high-throughput-sequencingsource · NCBI GEOconnector:ncbi_geo@1.0.0/gdstype
concepts[organism].NCBITaxon:10090source · NCBI GEOconnector:ncbi_geo@1.0.0/taxon
descriptionsource · NCBI GEOconnector:ncbi_geo@1.0.0/summary
publication_datesource · NCBI GEOconnector:ncbi_geo@1.0.0
titlesource · NCBI GEOconnector:ncbi_geo@1.0.0/title