Data · dataset · 2025
Optimizing standardized lab-grown skin substitutes reveals a proliferation-differentiation switch based in ascorbic acid
Listed in e-cienciaDatos
The project "From 2D to 3D: Optimization of lab-grown skin substitutes reveals a physiological switch based on ascorbic acid." aimed to provide culture conditioning and adjusting of keratinocytes intended to be used in differentiation processes.
Description
The keratinocytes were evaluated on their capacity to generate competent skin constructs as a model of cellular differentiation. The influence of ascorbic acid in 2D and 3D epidermal models was characterized, as it was found to act as a physiological switch.
This dataset comprises raw images obtained in the 2D and 3D analysis. The keratinocytes used correspond to HaCaT cells cultured under low calcium conditions. The results associated with FACS results should be carefully analyzed considering the differentiation trigger caused by detachment of the cells.
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For more information please refer to the related publications associated to this dataset.
Links
Where it is published
- Dataverse dataset page edatos.consorciomadrono.es/dataset.xhtml?persistentId=doi%3A10.21950%2FBUUT5Q ↗
landing page · from edatos consorciomadrono es
- DOI doi.org/10.21950/buut5q ↗
DOI / persistent id · from edatos consorciomadrono es
Catalogue records · 1
- Dataverse API edatos.consorciomadrono.es/api/datasets/:persistentId/?persistentId=doi%3A10.21950%2FBUUT… ↗
metadata API · from edatos consorciomadrono es
Topics
- Stated by source
- Ciencias médicas, de la salud y de la vida
- From keywords
- Medicine & Health
- Inferred from text
- Image 65% · Oncology and carcinogenesis 68%
Provenance · 1 source records, 10 field assertions
| Source | Key | Last seen | Raw |
|---|---|---|---|
| e-cienciaDatos | doi:10.21950/BUUT5Q | 12 d ago | JSON v1 |
| Field | Assertion | Extractor | Evidence |
|---|---|---|---|
| concepts[field].anzsrc:group:3211 | enrichment · edatos consorciomadrono es | taxonomy-embedding@1.1.0 | title+keywords+description (68%) |
| concepts[field].dataverse_subject:ciencias-m-dicas-de-la-salud-y-de-la-vida | source · edatos consorciomadrono es | connector:edatos_consorciomadrono_es@1.0.0 | /subjects |
| concepts[field].local:field:medicine-health | mapping · edatos consorciomadrono es | connector:edatos_consorciomadrono_es@1.0.0 | /subjects |
| concepts[modality].local:modality:image | enrichment · edatos consorciomadrono es | keyword-concept-rules@1.0.0 | title+description (65%) |
| created_date | source · edatos consorciomadrono es | connector:edatos_consorciomadrono_es@1.0.0 | |
| description | source · edatos consorciomadrono es | connector:edatos_consorciomadrono_es@1.0.0 | /description |
| publication_date | source · edatos consorciomadrono es | connector:edatos_consorciomadrono_es@1.0.0 | |
| title | source · edatos consorciomadrono es | connector:edatos_consorciomadrono_es@1.0.0 | /name |
| updated_date | source · edatos consorciomadrono es | connector:edatos_consorciomadrono_es@1.0.0 | |
| version_label | source · edatos consorciomadrono es | connector:edatos_consorciomadrono_es@1.0.0 |