Data · dataset · 2025
Replication data for - Incidence of loiasis clinical manifestations in a rural area of the Republic of Congo: results from a longitudinal prospective study (the MorLo project)
Listed in DataSuds
Loiasis is endemic in Central Africa.
Description
Despite evidence of clinical complications and increased mortality, it remains excluded from the list of neglected tropical diseases. The main manifestations are Calabar swellings (CS), Eyeworm (EW) and non-specific general symptoms such arthralgia and pruritus.
We calculated incidence rates for clinical manifestations of loiasis from a 13-month study on clinical manifestations in 991 individuals living in Loa loa-endemic areas in the Republic of Congo. From September 2022 to September 2023, community health workers collected weekly symptoms from cohort participants. Detailed data on symptom duration, intensity, associated pruritus, and impact on sleep were recorded.
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Laboratory procedures included thick blood smear for L. loa microfilaremia measurement, creatininemia measurement and eosinophilia counts. We used multiple failure analysis and frailty models to calculate incidence rates of EW, CS, arthralgia, pruritus and absence from work (AfW) and to analyses factors associated with increased incidence of each symptom. The population-attributable fractions (PAFs) associated with loiasis were also calculated for pruritus, AfW and arthralgia.
Links
Where it is published
- Dataverse dataset page dataverse.ird.fr/dataset.xhtml?persistentId=doi%3A10.23708%2FBNMZN8 ↗
landing page · from dataverse ird fr
- DOI doi.org/10.23708/bnmzn8 ↗
DOI / persistent id · from dataverse ird fr
Catalogue records · 1
- Dataverse API dataverse.ird.fr/api/datasets/:persistentId/?persistentId=doi%3A10.23708%2FBNMZ… ↗
metadata API · from dataverse ird fr
Topics
- Stated by source
- Medicine, Health and Life Sciences
- From keywords
- Life Sciences · Medicine & Health
- Inferred from text
- Longitudinal study 65%
Provenance · 1 source records, 10 field assertions
| Source | Key | Last seen | Raw |
|---|---|---|---|
| DataSuds | doi:10.23708/BNMZN8 | 13 d ago | JSON v1 |
| Field | Assertion | Extractor | Evidence |
|---|---|---|---|
| concepts[field].dataverse_subject:medicine-health-and-life-sciences | source · dataverse ird fr | connector:dataverse_ird_fr@1.0.0 | /subjects |
| concepts[field].local:field:life-sciences | mapping · dataverse ird fr | connector:dataverse_ird_fr@1.0.0 | /subjects |
| concepts[field].local:field:medicine-health | mapping · dataverse ird fr | connector:dataverse_ird_fr@1.0.0 | /subjects |
| concepts[method].local:method:longitudinal-study | enrichment · dataverse ird fr | keyword-concept-rules@1.0.0 | title+description (65%) |
| created_date | source · dataverse ird fr | connector:dataverse_ird_fr@1.0.0 | |
| description | source · dataverse ird fr | connector:dataverse_ird_fr@1.0.0 | /description |
| publication_date | source · dataverse ird fr | connector:dataverse_ird_fr@1.0.0 | |
| title | source · dataverse ird fr | connector:dataverse_ird_fr@1.0.0 | /name |
| updated_date | source · dataverse ird fr | connector:dataverse_ird_fr@1.0.0 | |
| version_label | source · dataverse ird fr | connector:dataverse_ird_fr@1.0.0 |