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Omics · study · 2026

Time-Resolved Single-Nucleus Transcriptomic Mapping of Neuro–Glial–Vascular Communication in the Hyperacute-to-Acute Stages of Optic Nerve Injury

Listed in NCBI GEO

Single-nucleus RNA-seq across six early time points after optic-nerve injury reveals a rapid, week-long shift in neuro-glial-vascular signaling: Müller glia, endothelial cells, and microglia pivot from pro-inflammatory to reparative programs.

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Expression profiling by high throughput sequencing · Mus musculus
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Life Sciences
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Biochemistry and cell biology 70% · RNA sequencing 65% · Single-cell RNA sequencing 65%
Provenance · 1 source records, 10 field assertions
SourceKeyLast seenRaw
NCBI GEOGSE30470915 d agoJSON v1
FieldAssertionExtractorEvidence
access_levelsource · NCBI GEOconnector:ncbi_geo@1.0.0
concepts[field].anzsrc:group:3101enrichment · NCBI GEOtaxonomy-embedding@1.1.0title+keywords+description (70%)
concepts[field].local:field:life-sciencesmapping · NCBI GEOconnector:ncbi_geo@1.0.0
concepts[method].geo_series_type:expression-profiling-by-high-throughput-sequencingsource · NCBI GEOconnector:ncbi_geo@1.0.0/gdstype
concepts[modality].local:modality:rna-seqenrichment · NCBI GEOkeyword-concept-rules@1.0.0title+description (65%)
concepts[modality].local:modality:single-cell-rna-seqenrichment · NCBI GEOkeyword-concept-rules@1.0.0title+description (65%)
concepts[organism].NCBITaxon:10090source · NCBI GEOconnector:ncbi_geo@1.0.0/taxon
descriptionsource · NCBI GEOconnector:ncbi_geo@1.0.0/summary
publication_datesource · NCBI GEOconnector:ncbi_geo@1.0.0
titlesource · NCBI GEOconnector:ncbi_geo@1.0.0/title