Table · study · 2026
Spatially resolved single-cell transcriptomic profiling of human lung adenocarcinoma and normal lung tissue using NanoString CosMx SMI
Listed in NCBI GEO
This study used the NanoString CosMx Spatial Molecular Imager (SMI) to perform spatially resolved single-cell transcriptomic profiling of human lung tissue.
Description
Three lung adenocarcinoma tissue specimens and three normal lung tissue specimens were analyzed. CosMx SMI enabled in situ detection and spatial localization of RNA transcripts at single-cell and subcellular resolution.
The processed dataset includes per-cell gene expression matrices, transcript coordinates, cell metadata, field-of-view (FOV) positions, and cell segmentation polygon data, providing a resource for investigating spatial cellular heterogeneity and the tumor microenvironment in lung adenocarcinoma.
Links
Get the data
- GEO FTP directory ftp.ncbi.nlm.nih.gov/geo/series/GSE346nnn/GSE346380 ↗
download · from NCBI GEO
Where it is published
- GEO accession page ncbi.nlm.nih.gov/geo/query/acc.cgi?acc=GSE346380 ↗
landing page · from NCBI GEO
Documentation and papers
- PRJNA1525231 ncbi.nlm.nih.gov/bioproject/PRJNA1525231 ↗
project · from NCBI GEO
Topics
- Stated by source
- Homo sapiens · Other
- From keywords
- Life Sciences
- Inferred from text
- Bioinformatics and computational biology 68% · Cancer 65%
Provenance · 1 source records, 9 field assertions
| Source | Key | Last seen | Raw |
|---|---|---|---|
| NCBI GEO | GSE346380 | 15 d ago | JSON v1 |
| Field | Assertion | Extractor | Evidence |
|---|---|---|---|
| access_level | source · NCBI GEO | connector:ncbi_geo@1.0.0 | |
| concepts[disease].local:disease:cancer | enrichment · NCBI GEO | keyword-concept-rules@1.0.0 | title+description (65%) |
| concepts[field].anzsrc:group:3102 | enrichment · NCBI GEO | taxonomy-embedding@1.1.0 | title+keywords+description (68%) |
| concepts[field].local:field:life-sciences | mapping · NCBI GEO | connector:ncbi_geo@1.0.0 | |
| concepts[method].geo_series_type:other | source · NCBI GEO | connector:ncbi_geo@1.0.0 | /gdstype |
| concepts[organism].NCBITaxon:9606 | source · NCBI GEO | connector:ncbi_geo@1.0.0 | /taxon |
| description | source · NCBI GEO | connector:ncbi_geo@1.0.0 | /summary |
| publication_date | source · NCBI GEO | connector:ncbi_geo@1.0.0 | |
| title | source · NCBI GEO | connector:ncbi_geo@1.0.0 | /title |