Data · dataset · 2026
Mechanisms of IKZF3 action in a variety of tumors
Listed in ScienceDB
Notes: c-myc: It is both a transposable gene and a regulatable gene regulated by multiple substances, and it is also a gene that enables cells to proliferate indefinitely, achieving immortalization, and promoting cell division.
Description
It is related to the occurrence and development of various tumors; IRF4: Interferon regulatory factor 4; ISG: Interferon-stimulated gene; MMP16: Matrix protease, which can degrade various protein components of the cell matrix; Twist: An evolutionarily highly conserved basic helix-loop-helix transcription factor, highly expressed in various malignant tumors, and has biological functions such as inducing epithelial-mesenchymal transition, promoting cell migration and invasion, and enhancing the resistance of chemotherapy drugs; BRD4: Regulates the transcription of multiple genes by binding to the promoter region; SHIP1: A negative regulator of PI3K/AKT signaling in hematopoietic cells.
Links
Where it is published
- DOI doi.org/10.57760/sciencedb.xbyxb.00173 ↗
DOI / persistent id · from scidb cn
Catalogue records · 1
- OAI-PMH record scidb.cn/oai?verb=GetRecord&metadataPrefix=oai_dc&identifier=10.57760%2… ↗
metadata API · from scidb cn
Topics
- From keywords
- Earth & Environmental Science · Engineering · Humanities · Life Sciences · Social Science
Provenance · 1 source records, 10 field assertions
| Source | Key | Last seen | Raw |
|---|---|---|---|
| ScienceDB | 10.57760/sciencedb.xbyxb.00173 | 12 d ago | JSON v1 |
| Field | Assertion | Extractor | Evidence |
|---|---|---|---|
| access_level | source · scidb cn | connector:scidb_cn@1.0.0 | |
| concepts[field].local:field:earth-environmental | mapping · scidb cn | connector:scidb_cn@1.0.0 | |
| concepts[field].local:field:engineering | mapping · scidb cn | connector:scidb_cn@1.0.0 | |
| concepts[field].local:field:humanities | mapping · scidb cn | connector:scidb_cn@1.0.0 | |
| concepts[field].local:field:life-sciences | mapping · scidb cn | connector:scidb_cn@1.0.0 | |
| concepts[field].local:field:social-science | mapping · scidb cn | connector:scidb_cn@1.0.0 | |
| description | source · scidb cn | connector:scidb_cn@1.0.0 | /metadata/dc/description |
| license | source · scidb cn | connector:scidb_cn@1.0.0 | /metadata/dc/rights |
| publication_date | source · scidb cn | connector:scidb_cn@1.0.0 | |
| title | source · scidb cn | connector:scidb_cn@1.0.0 | /metadata/dc/title |