Omics · study · 2026
Single-cell transcriptomics reveals markers of regulatory T cell dysfunction in Gestational Diabetes Mellitus
Listed in NCBI GEO
Gestational Diabetes Mellitus (GDM) is a common pregnancy complication and the role of regulatory T cells (Tregs) in this disease is ambiguous.
Description
This study aims to determine the aberrant transcriptional landscape in Tregs from GDM patients and controls. We identify gene expression programmes dysregulated in GDM Tregs and assess their utlilty as GDM biomarkers in bulk mRNA.
Links
Get the data
- GEO FTP directory ftp.ncbi.nlm.nih.gov/geo/series/GSE280nnn/GSE280975 ↗
download · from NCBI GEO
Where it is published
- GEO accession page ncbi.nlm.nih.gov/geo/query/acc.cgi?acc=GSE280975 ↗
landing page · from NCBI GEO
Documentation and papers
- PRJNA1181753 ncbi.nlm.nih.gov/bioproject/PRJNA1181753 ↗
project · from NCBI GEO
- PubMed 41933176 pubmed.ncbi.nlm.nih.gov/41933176 ↗
publication · from NCBI GEO
Topics
- Stated by source
- Expression profiling by high throughput sequencing · Homo sapiens · Other
- From keywords
- Life Sciences
- Inferred from text
- Disease 75%
Provenance · 1 source records, 9 field assertions
| Source | Key | Last seen | Raw |
|---|---|---|---|
| NCBI GEO | GSE280975 | 15 d ago | JSON v1 |
| Field | Assertion | Extractor | Evidence |
|---|---|---|---|
| access_level | source · NCBI GEO | connector:ncbi_geo@1.0.0 | |
| concepts[disease].local:disease:disease | enrichment · NCBI GEO | keyword-concept-rules@1.0.0 | title+description (75%) |
| concepts[field].local:field:life-sciences | mapping · NCBI GEO | connector:ncbi_geo@1.0.0 | |
| concepts[method].geo_series_type:expression-profiling-by-high-throughput-sequencing | source · NCBI GEO | connector:ncbi_geo@1.0.0 | /gdstype |
| concepts[method].geo_series_type:other | source · NCBI GEO | connector:ncbi_geo@1.0.0 | /gdstype |
| concepts[organism].NCBITaxon:9606 | source · NCBI GEO | connector:ncbi_geo@1.0.0 | /taxon |
| description | source · NCBI GEO | connector:ncbi_geo@1.0.0 | /summary |
| publication_date | source · NCBI GEO | connector:ncbi_geo@1.0.0 | |
| title | source · NCBI GEO | connector:ncbi_geo@1.0.0 | /title |