Omics · study · 2026
Strong Concordance of DNA Methylation Measures Between Venous and Capillary Blood - Implications for Human Epigenome Studies
Listed in NCBI GEO
DNA methylation is tissue specific, which has profound implications for data analysis.
Description
While both capillary and venous blood samples are whole blood, they are not identical in their clinical profiles. Here we assess the congruency of DNA methylation from 20 individuals with matched venous and capillary blood draw DNA methylation.
We used DNA methylation profiles from Illumina EPIC v2 arrays assess the differences of these blood sources in quality control approches, in predicted immune cell proportions, in DNA methylation based predictors including epigenetic clocks and lifestyle predictors, and performed an examplar EWAS
Links
Get the data
- GEO FTP directory ftp.ncbi.nlm.nih.gov/geo/series/GSE312nnn/GSE312123 ↗
download · from NCBI GEO
Where it is published
- GEO accession page ncbi.nlm.nih.gov/geo/query/acc.cgi?acc=GSE312123 ↗
landing page · from NCBI GEO
Documentation and papers
- PRJNA1372206 ncbi.nlm.nih.gov/bioproject/PRJNA1372206 ↗
project · from NCBI GEO
- PubMed 42181266 pubmed.ncbi.nlm.nih.gov/42181266 ↗
publication · from NCBI GEO
Topics
- Stated by source
- Genome binding/occupancy profiling by genome tiling array · Homo sapiens
- From keywords
- Life Sciences
- Inferred from text
- Genetics 70%
Provenance · 1 source records, 8 field assertions
| Source | Key | Last seen | Raw |
|---|---|---|---|
| NCBI GEO | GSE312123 | 15 d ago | JSON v1 |
| Field | Assertion | Extractor | Evidence |
|---|---|---|---|
| access_level | source · NCBI GEO | connector:ncbi_geo@1.0.0 | |
| concepts[field].anzsrc:group:3105 | enrichment · NCBI GEO | taxonomy-embedding@1.1.0 | title+keywords+description (70%) |
| concepts[field].local:field:life-sciences | mapping · NCBI GEO | connector:ncbi_geo@1.0.0 | |
| concepts[method].geo_series_type:genome-binding-occupancy-profiling-by-genome-tiling-array | source · NCBI GEO | connector:ncbi_geo@1.0.0 | /gdstype |
| concepts[organism].NCBITaxon:9606 | source · NCBI GEO | connector:ncbi_geo@1.0.0 | /taxon |
| description | source · NCBI GEO | connector:ncbi_geo@1.0.0 | /summary |
| publication_date | source · NCBI GEO | connector:ncbi_geo@1.0.0 | |
| title | source · NCBI GEO | connector:ncbi_geo@1.0.0 | /title |