Omics · study · 2026
Transcriptomics of THP-1-derived macrophages infected with mycobacteria
Listed in NCBI GEO
Description
Transcriptomic profiling was performed on PMA-differentiated THP-1-derived human macrophages to investigate host transcriptional responses to infection with novel mycobacterial species (Mycobacterium camsae, Mycobacterium pumcae) in comparison with known reference strains (Mycobacterium gordonae, Mycobacterium abscessus, Mycobacterium marinum). This dataset provides insights into host-pathogen interactions and identifies key differentially expressed genes and pathways involved in macrophage responses to mycobacterial infection.
Links
Get the data
- GEO FTP directory ftp.ncbi.nlm.nih.gov/geo/series/GSE328nnn/GSE328953 ↗
download · from NCBI GEO
Where it is published
- GEO accession page ncbi.nlm.nih.gov/geo/query/acc.cgi?acc=GSE328953 ↗
landing page · from NCBI GEO
Documentation and papers
- PRJNA1455367 ncbi.nlm.nih.gov/bioproject/PRJNA1455367 ↗
project · from NCBI GEO
- PubMed 42245512 pubmed.ncbi.nlm.nih.gov/42245512 ↗
publication · from NCBI GEO
Topics
- Stated by source
- Expression profiling by high throughput sequencing · Homo sapiens
- From keywords
- Life Sciences
- Inferred from text
- Bioinformatics and computational biology 69%
Provenance · 1 source records, 8 field assertions
| Source | Key | Last seen | Raw |
|---|---|---|---|
| NCBI GEO | GSE328953 | 15 d ago | JSON v1 |
| Field | Assertion | Extractor | Evidence |
|---|---|---|---|
| access_level | source · NCBI GEO | connector:ncbi_geo@1.0.0 | |
| concepts[field].anzsrc:group:3102 | enrichment · NCBI GEO | taxonomy-embedding@1.1.0 | title+keywords+description (69%) |
| concepts[field].local:field:life-sciences | mapping · NCBI GEO | connector:ncbi_geo@1.0.0 | |
| concepts[method].geo_series_type:expression-profiling-by-high-throughput-sequencing | source · NCBI GEO | connector:ncbi_geo@1.0.0 | /gdstype |
| concepts[organism].NCBITaxon:9606 | source · NCBI GEO | connector:ncbi_geo@1.0.0 | /taxon |
| description | source · NCBI GEO | connector:ncbi_geo@1.0.0 | /summary |
| publication_date | source · NCBI GEO | connector:ncbi_geo@1.0.0 | |
| title | source · NCBI GEO | connector:ncbi_geo@1.0.0 | /title |