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Omics · study · 2026

Compare the transcriptomic effects of FK228 and Class I HDACs YF mutants overexpression

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To compare the transcriptomic effects of FK228 and Class I HDACs YF mutants overexpression and to characterize their inter-dependency, we performed RNA-seq in AML12 cells in the above-mentioned 4 groups: control, FK228, YF overexpression, and FK228 + YF overexpression.

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Expression profiling by high throughput sequencing · Mus musculus
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Life Sciences
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Genetics 69% · RNA sequencing 65%
Provenance · 1 source records, 9 field assertions
SourceKeyLast seenRaw
NCBI GEOGSE27609415 d agoJSON v1
FieldAssertionExtractorEvidence
access_levelsource · NCBI GEOconnector:ncbi_geo@1.0.0
concepts[field].anzsrc:group:3105enrichment · NCBI GEOtaxonomy-embedding@1.1.0title+keywords+description (69%)
concepts[field].local:field:life-sciencesmapping · NCBI GEOconnector:ncbi_geo@1.0.0
concepts[method].geo_series_type:expression-profiling-by-high-throughput-sequencingsource · NCBI GEOconnector:ncbi_geo@1.0.0/gdstype
concepts[modality].local:modality:rna-seqenrichment · NCBI GEOkeyword-concept-rules@1.0.0title+description (65%)
concepts[organism].NCBITaxon:10090source · NCBI GEOconnector:ncbi_geo@1.0.0/taxon
descriptionsource · NCBI GEOconnector:ncbi_geo@1.0.0/summary
publication_datesource · NCBI GEOconnector:ncbi_geo@1.0.0
titlesource · NCBI GEOconnector:ncbi_geo@1.0.0/title