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Omics · study · 2026

Long FAM13A isoforms regulate human lung epithelial development in vitro

Listed in NCBI GEO

We performed single cell transcriptomic profiling of induced human pluripotent stem cells (iPSCs)-derived anterior foregut progenitors (D6) and lung progenitors (D15).

Description

FAM13A-long isoforms were knocked out of iPSCs prior to differentiation. Prior to capture, cells were labelled with hashing antibodies (HTO).

Cells were captured for 10x Genomics Single cell capture (V3 protocol), and GEX and HTO libraries were sequenced. HTODemux function was used to demultiplex the samples. FAM13A-long KO changed clustering of D15 NKX2-1+ lung progenitors

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Life Sciences
Provenance · 1 source records, 8 field assertions
SourceKeyLast seenRaw
NCBI GEOGSE30621015 d agoJSON v1
FieldAssertionExtractorEvidence
access_levelsource · NCBI GEOconnector:ncbi_geo@1.0.0
concepts[field].local:field:life-sciencesmapping · NCBI GEOconnector:ncbi_geo@1.0.0
concepts[method].geo_series_type:expression-profiling-by-high-throughput-sequencingsource · NCBI GEOconnector:ncbi_geo@1.0.0/gdstype
concepts[method].geo_series_type:othersource · NCBI GEOconnector:ncbi_geo@1.0.0/gdstype
concepts[organism].NCBITaxon:9606source · NCBI GEOconnector:ncbi_geo@1.0.0/taxon
descriptionsource · NCBI GEOconnector:ncbi_geo@1.0.0/summary
publication_datesource · NCBI GEOconnector:ncbi_geo@1.0.0
titlesource · NCBI GEOconnector:ncbi_geo@1.0.0/title