Omics · study · 2026
SnRNA-seq, snATAC-seq and Stereo-seq datasets of mouse striatum at different time points in MCAO/R
Listed in NCBI GEO
Ischemic stroke constitutes a multifaceted neurological affliction involving diverse cell types in the brain.
Description
A lack of dynamic transcriptional and chromatin accessibility data in the post-stroke period remains a key barrier to elucidating the underlying mechanisms. We employed snRNA-seq, snATAC-seq and Stereo-seq to construct a comprehensive transcriptional and chromatin accessibility landscape of the striatum covering the acute (0 h), subacute (24 h), and chronic (7 d, 14 d) phases post-MCAO/R mice.
Links
Get the data
- GEO FTP directory ftp.ncbi.nlm.nih.gov/geo/series/GSE332nnn/GSE332910 ↗
download · from NCBI GEO
Where it is published
- GEO accession page ncbi.nlm.nih.gov/geo/query/acc.cgi?acc=GSE332910 ↗
landing page · from NCBI GEO
Documentation and papers
- PRJNA1469465 ncbi.nlm.nih.gov/bioproject/PRJNA1469465 ↗
project · from NCBI GEO
- PubMed 42693582 pubmed.ncbi.nlm.nih.gov/42693582 ↗
publication · from NCBI GEO
Topics
- Stated by source
- Expression profiling by high throughput sequencing · Genome binding/occupancy profiling by high throughput sequencing · Mus musculus
- From keywords
- Life Sciences
- Inferred from text
- Biochemistry and cell biology 71% · Single-cell RNA sequencing 65%
Provenance · 1 source records, 10 field assertions
| Source | Key | Last seen | Raw |
|---|---|---|---|
| NCBI GEO | GSE332910 | 15 d ago | JSON v1 |
| Field | Assertion | Extractor | Evidence |
|---|---|---|---|
| access_level | source · NCBI GEO | connector:ncbi_geo@1.0.0 | |
| concepts[field].anzsrc:group:3101 | enrichment · NCBI GEO | taxonomy-embedding@1.1.0 | title+keywords+description (71%) |
| concepts[field].local:field:life-sciences | mapping · NCBI GEO | connector:ncbi_geo@1.0.0 | |
| concepts[method].geo_series_type:expression-profiling-by-high-throughput-sequencing | source · NCBI GEO | connector:ncbi_geo@1.0.0 | /gdstype |
| concepts[method].geo_series_type:genome-binding-occupancy-profiling-by-high-throughput-sequencing | source · NCBI GEO | connector:ncbi_geo@1.0.0 | /gdstype |
| concepts[modality].local:modality:single-cell-rna-seq | enrichment · NCBI GEO | keyword-concept-rules@1.0.0 | title+description (65%) |
| concepts[organism].NCBITaxon:10090 | source · NCBI GEO | connector:ncbi_geo@1.0.0 | /taxon |
| description | source · NCBI GEO | connector:ncbi_geo@1.0.0 | /summary |
| publication_date | source · NCBI GEO | connector:ncbi_geo@1.0.0 | |
| title | source · NCBI GEO | connector:ncbi_geo@1.0.0 | /title |