Data · dataset · 2026
<p><i>MARCHF5</i> is a co-dependent oncogene with <i>MCL1</i> in PEL cell lines.</p>
Listed in UCL Research Data Repository
Description
<p>A-B. Top co- and anti-dependencies of A. <i>MCL1</i> or B. <i>MARCHF5</i> from the Cancer Dependency Map 23Q4. The top 100 genes are listed in <a href="plospathogens.org/article/info:doi/10.1371/journal.ppat.1014665#ppat.1014665.s001" target="_blank">S1 Table</a>. C. Median fold changes of gRNAs targeting <i>MCL1</i> or <i>MARCHF5</i> in our gene essentiality CRISPR screens in PEL cell lines [<a href="plospathogens.org/article/info:doi/10.1371/journal.ppat.1014665#ppat.1014665.ref015" target="_blank">15</a>].
D. Western blots of MARCHF5 in a panel of PEL cell lines that are infected with KSHV only or co-infected by KSHV and EBV.</p>
Links
Where it is published
- DOI doi.org/10.1371/journal.ppat.1014665.g001 ↗
DOI / persistent id · from rdr ucl ac uk
Catalogue records · 1
- OAI-PMH record api.figshare.com/v2/oai?verb=GetRecord&metadataPrefix=oai_dc&identifier=oai%3Af… ↗
metadata API · from rdr ucl ac uk
Topics
- From keywords
- Biochemistry and cell biology · Cancer · Earth & Environmental Science · Genetics · Infectious diseases · Life Sciences · Medicine & Health · Virology
- Inferred from text
- Tabular 65%
Provenance · 1 source records, 14 field assertions
| Source | Key | Last seen | Raw |
|---|---|---|---|
| UCL Research Data Repository | oai:figshare.com:article/34049117 | 12 d ago | JSON v1 |
| Field | Assertion | Extractor | Evidence |
|---|---|---|---|
| access_level | source · rdr ucl ac uk | connector:rdr_ucl_ac_uk@1.0.0 | |
| concepts[disease].local:disease:cancer | mapping · rdr ucl ac uk | vocabulary-mapper@1.0.0 | keywords['Cancer'] |
| concepts[field].anzsrc:field:310706 | mapping · rdr ucl ac uk | vocabulary-mapper@1.0.0 | keywords['Virology'] |
| concepts[field].anzsrc:field:320211 | mapping · rdr ucl ac uk | vocabulary-mapper@1.0.0 | keywords['Infectious Diseases'] |
| concepts[field].anzsrc:group:3101 | mapping · rdr ucl ac uk | vocabulary-mapper@1.0.0 | keywords['Cell Biology'] |
| concepts[field].anzsrc:group:3105 | mapping · rdr ucl ac uk | vocabulary-mapper@1.0.0 | keywords['Genetics'] |
| concepts[field].local:field:earth-environmental | mapping · rdr ucl ac uk | connector:rdr_ucl_ac_uk@1.0.0 | |
| concepts[field].local:field:life-sciences | mapping · rdr ucl ac uk | connector:rdr_ucl_ac_uk@1.0.0 | |
| concepts[field].local:field:medicine-health | mapping · rdr ucl ac uk | connector:rdr_ucl_ac_uk@1.0.0 | |
| concepts[modality].local:modality:tabular | enrichment · rdr ucl ac uk | keyword-concept-rules@1.0.0 | title+description (65%) |
| description | source · rdr ucl ac uk | connector:rdr_ucl_ac_uk@1.0.0 | /metadata/dc/description |
| license | source · rdr ucl ac uk | connector:rdr_ucl_ac_uk@1.0.0 | /metadata/dc/rights |
| publication_date | source · rdr ucl ac uk | connector:rdr_ucl_ac_uk@1.0.0 | |
| title | source · rdr ucl ac uk | connector:rdr_ucl_ac_uk@1.0.0 | /metadata/dc/title |