<i>CircARID1A</i> promotes gastric cancer progression by targeting the <i>miR-147a</i>/SNAI2 signaling axis

Dual-luciferase reporter assays, qPCR and Western blot were utilized to investigate the interactions between <i>circARID1A</i>, <i>miR-147a</i>, and <i>SNAI2</i>. <i>CircARID1A</i> promotes GC cell proliferation, migration, and invasion by regulating the <i>miR-147a</i>/SNAI2 axis. <i>In vivo</i>, knockdown of <i>circARID1A</i> inhibits tumor growth in subcutaneous xenograft models.</p> <p></p><p>Suppression of <i>circARID1A</i> significantly inhibits gastric cancer cell proliferation, migration, and invasion.</p><p><i>miR-147a</i> directly targets and negatively regulates SNAI2 expression, inhibiting its oncogenic effects.</p><p>CircARID1A promotes cell proliferation, migration, and invasion in gastric cancer cells through the <i>miR-147a/SNAI2</i> signaling axis.</p><p></p> <p>Suppression of <i>circARID1A</i> significantly inhibits gastric cancer cell proliferation, migration, and invasion.</p> <p><i>miR-147a</i> directly targets and negatively regulates SNAI2 expression, inhibiting its oncogenic effects.</p> <p>CircARID1A promotes cell proliferation, migration, and invasion in gastric cancer cells through the <i>miR-147a/SNAI2</i> signaling axis.</p>