Oral Bioavailability and Drug-Likeness Profiling of Gypenoside Derivatives Isolated from Gynostemma pentaphyllum

This dataset presents quantitative evaluations of 10 gypenoside compounds, reporting their oral bioavailability (OB, %) and drug-likeness (DL) scores—two critical metrics for preclinical drug candidate screening. The parameters summarized herein offer foundational data to assess the translational potential of these natural saponins for pharmaceutical development, facilitating subsequent structure-activity relationship (SAR) analyses and lead compound optimization.