Engineered core-shell immunomodulators for dual immune activation and sustained anti-MRSA protection via macrophage metabolic reprogramming

Artificial biofilm-coated nucleoshell immunomodulator (LM@HiSeL) is a novel immunomodulator designed to achieve precise modulation of the body's immune system through its unique nucleoshell structure and biofilm coating, in order to enhance the body's defenses against pathogens (e.g., methicillin-resistant Staphylococcus aureus, MRSA). This database aims to systematically document the comprehensive properties of LM@HiSeL, including key information on its characterization, safety, stability, bioactivity assessment, and mechanism of action, so as to provide data support for subsequent research and clinical applications.