Excel · study · 2026
A Neutrophil–Mesangial Cell Axis Promotes Glomerular Injury in Lupus Nephritis
Listed in NCBI GEO
Neutrophil extracellular trap (NET)-producing neutrophils infiltrate the kidney early in lupus nephritis (LN).
Description
NET-derived citrullinated histone H3 activates mesangial cells (MCs) through TLR4, promoting inflammation and fibrosis, establishing a novel NET–MC axis that may represent a mechanistic driver and therapeutic target in LN.
Links
Get the data
- GEO FTP directory ftp.ncbi.nlm.nih.gov/geo/series/GSE310nnn/GSE310054 ↗
download · from NCBI GEO
Where it is published
- GEO accession page ncbi.nlm.nih.gov/geo/query/acc.cgi?acc=GSE310054 ↗
landing page · from NCBI GEO
Documentation and papers
- PRJNA1365062 ncbi.nlm.nih.gov/bioproject/PRJNA1365062 ↗
project · from NCBI GEO
- PubMed 41354562 pubmed.ncbi.nlm.nih.gov/41354562 ↗
publication · from NCBI GEO
Topics
- Stated by source
- Expression profiling by high throughput sequencing · Homo sapiens
- From keywords
- Life Sciences
Provenance · 1 source records, 7 field assertions
| Source | Key | Last seen | Raw |
|---|---|---|---|
| NCBI GEO | GSE310054 | 15 d ago | JSON v1 |
| Field | Assertion | Extractor | Evidence |
|---|---|---|---|
| access_level | source · NCBI GEO | connector:ncbi_geo@1.0.0 | |
| concepts[field].local:field:life-sciences | mapping · NCBI GEO | connector:ncbi_geo@1.0.0 | |
| concepts[method].geo_series_type:expression-profiling-by-high-throughput-sequencing | source · NCBI GEO | connector:ncbi_geo@1.0.0 | /gdstype |
| concepts[organism].NCBITaxon:9606 | source · NCBI GEO | connector:ncbi_geo@1.0.0 | /taxon |
| description | source · NCBI GEO | connector:ncbi_geo@1.0.0 | /summary |
| publication_date | source · NCBI GEO | connector:ncbi_geo@1.0.0 | |
| title | source · NCBI GEO | connector:ncbi_geo@1.0.0 | /title |