Omics · study · 2026
Transcriptome regulation in T-cells and monocytes in patients with Common Variable Immunodeficiency
Listed in NCBI GEO
A large subgroup of Common Variable Immunodeficiency (CVID) patients has autoimmune and inflammatory complications, associated with T cell and monocyte pathology, but the molecular mechanism for this CVID-subgroup is still elusive.
Description
To identify novel molecular pathways impacted in CVID T cells and monocytes, we examined the transcriptomic profiles in these cells from healthy control and the CVID patients in the subgroup with inflammatory complications.
Links
Get the data
- GEO FTP directory ftp.ncbi.nlm.nih.gov/geo/series/GSE299nnn/GSE299706 ↗
download · from NCBI GEO
Where it is published
- GEO accession page ncbi.nlm.nih.gov/geo/query/acc.cgi?acc=GSE299706 ↗
landing page · from NCBI GEO
Documentation and papers
- PRJNA1276100 ncbi.nlm.nih.gov/bioproject/PRJNA1276100 ↗
project · from NCBI GEO
- PubMed 41991796 pubmed.ncbi.nlm.nih.gov/41991796 ↗
publication · from NCBI GEO
Topics
- Stated by source
- Expression profiling by high throughput sequencing · Homo sapiens
- From keywords
- Life Sciences
Provenance · 1 source records, 7 field assertions
| Source | Key | Last seen | Raw |
|---|---|---|---|
| NCBI GEO | GSE299706 | 14 d ago | JSON v1 |
| Field | Assertion | Extractor | Evidence |
|---|---|---|---|
| access_level | source · NCBI GEO | connector:ncbi_geo@1.0.0 | |
| concepts[field].local:field:life-sciences | mapping · NCBI GEO | connector:ncbi_geo@1.0.0 | |
| concepts[method].geo_series_type:expression-profiling-by-high-throughput-sequencing | source · NCBI GEO | connector:ncbi_geo@1.0.0 | /gdstype |
| concepts[organism].NCBITaxon:9606 | source · NCBI GEO | connector:ncbi_geo@1.0.0 | /taxon |
| description | source · NCBI GEO | connector:ncbi_geo@1.0.0 | /summary |
| publication_date | source · NCBI GEO | connector:ncbi_geo@1.0.0 | |
| title | source · NCBI GEO | connector:ncbi_geo@1.0.0 | /title |