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Data · dataset · 2026

Based on Network Pharmacology and Experimental Verification to Explore the Mechanism of Guizhi‑Jialong‑Muli Decoction in the Treatment of Insomnia

Listed in ScienceDB

This research data covers multi-dimensional indicators such as neuroinflammatory markers (IBA, GFAP), neurotransmitters (5-HT, GLU), inflammatory factors (TNF - α, IL-6, IL-1 β), protein expression (AKT, P-AKT, PI3K, P-PI3K), and open field behavioral tests.

Description

All tables are set with six unified experimental groups: Control (blank control group), Model (disease model group), Estazolam (positive control group of estazolam), GZJLMT-L/M/H (Guizhi Jialonggu Oyster soup GZJLMT low, medium, and high dose groups).

In terms of the number of records, the IBA, GFAP, and 5-HT tables each contain 6 repeated experimental data; The TNF - α, IL-6, IL-1 β, and GLU tables each contain 12 items (6 for serum and 6 for tissue samples); The open field data table contains 24 items, divided into two groups of "central dwell time" and "central dwell frequency" (12 items each), with behavioral labels ranging from experimental numbers Exp_1 to Exp_12.

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All experiments were conducted with 6 or 12 biological replicates to ensure data reliability. Some table column names have slight formatting differences (such as hyphens and underscores), but the group meanings are consistent. 

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Where it is published

Catalogue records · 1

Topics

Inferred from text
Disease 75% · Tabular 65%
Provenance · 1 source records, 13 field assertions
SourceKeyLast seenRaw
ScienceDB10.57760/sciencedb.nprd.0003812 d agoJSON v1
FieldAssertionExtractorEvidence
access_levelsource · scidb cnconnector:scidb_cn@1.0.0
concepts[disease].local:disease:diseaseenrichment · scidb cnkeyword-concept-rules@1.0.0title+description (75%)
concepts[field].local:field:earth-environmentalmapping · scidb cnconnector:scidb_cn@1.0.0
concepts[field].local:field:engineeringmapping · scidb cnconnector:scidb_cn@1.0.0
concepts[field].local:field:humanitiesmapping · scidb cnconnector:scidb_cn@1.0.0
concepts[field].local:field:life-sciencesmapping · scidb cnconnector:scidb_cn@1.0.0
concepts[field].local:field:medicine-healthmapping · scidb cnconnector:scidb_cn@1.0.0
concepts[field].local:field:social-sciencemapping · scidb cnconnector:scidb_cn@1.0.0
concepts[modality].local:modality:tabularenrichment · scidb cnkeyword-concept-rules@1.0.0title+description (65%)
descriptionsource · scidb cnconnector:scidb_cn@1.0.0/metadata/dc/description
license_textsource · scidb cnconnector:scidb_cn@1.0.0
publication_datesource · scidb cnconnector:scidb_cn@1.0.0
titlesource · scidb cnconnector:scidb_cn@1.0.0/metadata/dc/title