An open source simulation package for coupled biomechanical and biochemical events

BMBC-Sim enables the definition of complex geometries, material properties, chemical species and their interactions, and the coupling of biochemical and mechanical processes through partial differential equations (PDEs) solved using finite element methods.

The poster demonstrates the framework through benchmark problems and applications involving calcium dynamics, complex biological geometries, and concentration-dependent mechanical deformation.</p><p dir="ltr"><br></p><p dir="ltr">Presented at Biology and Engineering of the Cell Surface, HHMI Janelia</p><p dir="ltr">Research Campus, Ashburn, Virginia, USA, October 2025.</p>