Omics · study · 2026
Global transcriptional profile of the UV-treated Zdr1 deletion mutant, a gene involved in the maintenance of genome integrity in Ustilago maydis
Listed in NCBI GEO
Given that Zdr1- the protein we previously identified (Azanjac et al., 2024) is a nuclear protein containing Zn-finger domain, and binds to dsDNA, we investigated possibility of its role in regulation of gene expression.
Description
We analysed differentially expressed genes in wt and ∆zdr1 cells upon UV treatment. Since no transcriptomic datasets have yet been reported for Ustilago maydis in response to UV irradiation, we first performed a comprehensive transcriptome analysis of wild-type cells exposed to UV and subsequently recovered for 1 h in growth medium.
This profiling established the foundation for further analysis of ∆zdr1-specific transcriptional response.
Links
Get the data
- GEO FTP directory ftp.ncbi.nlm.nih.gov/geo/series/GSE346nnn/GSE346861 ↗
download · from NCBI GEO
Where it is published
- GEO accession page ncbi.nlm.nih.gov/geo/query/acc.cgi?acc=GSE346861 ↗
landing page · from NCBI GEO
Documentation and papers
- PRJNA1526739 ncbi.nlm.nih.gov/bioproject/PRJNA1526739 ↗
project · from NCBI GEO
Topics
- Stated by source
- Expression profiling by high throughput sequencing
- From keywords
- Life Sciences
- Inferred from text
- Genetics 69%
Provenance · 1 source records, 7 field assertions
| Source | Key | Last seen | Raw |
|---|---|---|---|
| NCBI GEO | GSE346861 | 14 d ago | JSON v1 |
| Field | Assertion | Extractor | Evidence |
|---|---|---|---|
| access_level | source · NCBI GEO | connector:ncbi_geo@1.0.0 | |
| concepts[field].anzsrc:group:3105 | enrichment · NCBI GEO | taxonomy-embedding@1.1.0 | title+keywords+description (69%) |
| concepts[field].local:field:life-sciences | mapping · NCBI GEO | connector:ncbi_geo@1.0.0 | |
| concepts[method].geo_series_type:expression-profiling-by-high-throughput-sequencing | source · NCBI GEO | connector:ncbi_geo@1.0.0 | /gdstype |
| description | source · NCBI GEO | connector:ncbi_geo@1.0.0 | /summary |
| publication_date | source · NCBI GEO | connector:ncbi_geo@1.0.0 | |
| title | source · NCBI GEO | connector:ncbi_geo@1.0.0 | /title |