Omics · study · 2026
ACSS2 aggravates Metabolic dysfunction associated steatohepatitis (MASH) by regulating AIF1 mediated inflammation
Listed in NCBI GEO
Metabolic dysfunction associated steatohepatitis (MASH) is one of the most common types of liver disease, which is caused by hepatotoxicity caused by metabolic disorder.
Description
The incidence rate and mortality are very high, but the current treatment drugs are still limited. The role of ACSS2 in regulating inflammation in MASH is unclear.
This study aims to explore the role and potential mechanisms of ACSS2 in the progression of MASH.
Links
Get the data
- GEO FTP directory ftp.ncbi.nlm.nih.gov/geo/series/GSE310nnn/GSE310314 ↗
download · from NCBI GEO
Where it is published
- GEO accession page ncbi.nlm.nih.gov/geo/query/acc.cgi?acc=GSE310314 ↗
landing page · from NCBI GEO
Documentation and papers
- PRJNA1365757 ncbi.nlm.nih.gov/bioproject/PRJNA1365757 ↗
project · from NCBI GEO
- PubMed 42649158 pubmed.ncbi.nlm.nih.gov/42649158 ↗
publication · from NCBI GEO
Topics
- Stated by source
- Expression profiling by high throughput sequencing · Mus musculus
- From keywords
- Life Sciences
- Inferred from text
- Disease 75%
Provenance · 1 source records, 8 field assertions
| Source | Key | Last seen | Raw |
|---|---|---|---|
| NCBI GEO | GSE310314 | 15 d ago | JSON v1 |
| Field | Assertion | Extractor | Evidence |
|---|---|---|---|
| access_level | source · NCBI GEO | connector:ncbi_geo@1.0.0 | |
| concepts[disease].local:disease:disease | enrichment · NCBI GEO | keyword-concept-rules@1.0.0 | title+description (75%) |
| concepts[field].local:field:life-sciences | mapping · NCBI GEO | connector:ncbi_geo@1.0.0 | |
| concepts[method].geo_series_type:expression-profiling-by-high-throughput-sequencing | source · NCBI GEO | connector:ncbi_geo@1.0.0 | /gdstype |
| concepts[organism].NCBITaxon:10090 | source · NCBI GEO | connector:ncbi_geo@1.0.0 | /taxon |
| description | source · NCBI GEO | connector:ncbi_geo@1.0.0 | /summary |
| publication_date | source · NCBI GEO | connector:ncbi_geo@1.0.0 | |
| title | source · NCBI GEO | connector:ncbi_geo@1.0.0 | /title |