Cross-platform endothelial and angiogenic marker re-analysis in pterygium: eighteen-gene statistics

This dataset supports the companion manuscript submitted to Scientific Reports on a cross-platform endothelial and angiogenic marker re-analysis in pterygium.The primary table, EighteenGene_GSE2513_statistics.csv, provides the complete differential-expression statistics for the eighteen vascular, endothelial, hypoxia and lymphatic marker genes of the study panel in GSE2513 (pterygium n = 8 versus normal conjunctiva n = 4; GPL96 Affymetrix HG-U133A).

Values are at gene level, after median aggregation of multi-probe genes, and the probe used, the Welch t statistic, the nominal P value and the Benjamini-Hochberg adjusted P value are given for every gene. It is the electronic version of Table 1 of the manuscript.The package additionally contains: (i) a 24-gene x 5-dataset directional consistency matrix (GSE2513, GSE51995, GSE208384, GSE155776, PRJNA669964), which is a wider gene set than the study panel and should not be confused with it; (ii) independent-validation panel statistics for PRJNA669964, a cohort that took no part in dataset discovery; (iii) promoter-region methylation change (delta-beta) for GSE289869; (iv) supplementary analyses comprising pathway and cell-type scores, protein-protein interaction topology, per-cohort effect-size combination, and a hypothesis-generating drug-signature screen; and (v) all analysis scripts and all main and supplementary figure files.Nine public datasets in total are re-analysed.